InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Acaa1b

Summary

InnateDB Protein

IDBP-204424.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Acaa1b

Protein Name

acetyl-Coenzyme A acyltransferase 1B

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000010795

InnateDB Gene

IDBG-204422 (Acaa1b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Peroxisome {ECO:0000250}.

Disease Associations

Tissue Specificity

Mainly expressed in liver; weaker levels in kidney, intestine and white adipose tissue. {ECO:0000269PubMed:15043762}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003988	acetyl-CoA C-acyltransferase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

Biological Process

GO:0006631	fatty acid metabolic process
GO:0008152	metabolic process
GO:0008610	lipid biosynthetic process

Cellular Component

GO:0005739	mitochondrion
GO:0005777	peroxisome

Protein Structure and Domains

PDB ID

MGI:3605455

InterPro

IPR002155 Thiolase
IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal
IPR016039 Thiolase-like
IPR020616 Thiolase, N-terminal
IPR020617 Thiolase, C-terminal

PFAM

PF08541
PF00108
PF02803

PRINTS

PIRSF

PIRSF000429

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8VCH0