InnateDB Protein
|
IDBP-204773.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Rffl
|
Protein Name
|
ring finger and FYVE like domain containing protein
|
Synonyms
|
1700051E09Rik; 4930516L10Rik; BG080975; Carp2;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000071150
|
InnateDB Gene
|
IDBG-204769 (Rffl)
|
Protein Structure
|
|
Function |
|
Subcellular Localization |
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
0
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
13 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0006886
|
intracellular protein transport
|
GO:0010804
|
negative regulation of tumor necrosis factor-mediated signaling pathway
|
GO:0043161
|
proteasome-mediated ubiquitin-dependent protein catabolic process
|
GO:0070936
|
protein K48-linked ubiquitination
|
GO:1901797
|
negative regulation of signal transduction by p53 class mediator
|
GO:1902042
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:2001271
|
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
|
|
Cellular Component |
|
PDB ID |
MGI:1914588
|
InterPro |
IPR001841
Zinc finger, RING-type
IPR011011
Zinc finger, FYVE/PHD-type
|
PFAM |
PF13639
PF14634
|
PRINTS |
|
PIRSF |
|
SMART |
SM00184
|
TIGRFAMs |
|
Modification |
|
SwissProt |
|
PhosphoSite |
PhosphoSite-NP_001158041
|
TrEMBL |
Q6YAT6
|
UniProt Splice Variant |
|
Entrez Gene |
67338
|
UniGene |
Mm.341608
|
RefSeq |
NP_001158041
|
MGI ID |
|
MGI Symbol |
Rffl
|
OMIM |
|
CCDS |
CCDS48868
|
HPRD |
|
IMGT |
|
EMBL |
AK150213
AK150541
AL645594
AL646089
AY163902
AY163903
|
GenPept |
AAO42677
AAO42678
BAE29383
BAE29644
|
|
|