InnateDB Protein
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IDBP-204837.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gpat2
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Protein Name
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glycerol-3-phosphate acyltransferase 2, mitochondrial
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000049619
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InnateDB Gene
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IDBG-204835 (Gpat2)
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Protein Structure
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Function |
Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. {ECO:0000269PubMed:17013544, ECO:0000269PubMed:17689486}.
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Subcellular Localization |
Mitochondrion outer membrane {ECO:0000269PubMed:17013544, ECO:0000269PubMed:17689486, ECO:0000269PubMed:22285183}; Multi-pass membrane protein {ECO:0000269PubMed:17013544, ECO:0000269PubMed:17689486, ECO:0000269PubMed:22285183}.
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Disease Associations |
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Tissue Specificity |
Highly exprresed in the testis. Expressed at lower levels in the heart, liver, kidney, spleen and adipose cells. {ECO:0000269PubMed:17013544, ECO:0000269PubMed:17689486}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0004366
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glycerol-3-phosphate O-acyltransferase activity
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GO:0016746
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transferase activity, transferring acyl groups
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2684962
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InterPro |
IPR002123
Phospholipid/glycerol acyltransferase
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PFAM |
PF01553
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PRINTS |
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PIRSF |
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SMART |
SM00563
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TIGRFAMs |
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Modification |
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SwissProt |
Q14DK4
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PhosphoSite |
PhosphoSite-Q14DK4
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TrEMBL |
Q0KK35
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UniProt Splice Variant |
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Entrez Gene |
215456
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UniGene |
Mm.440454
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RefSeq |
NP_001074558
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MGI ID |
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MGI Symbol |
Gpat2
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OMIM |
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CCDS |
CCDS38232
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HPRD |
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IMGT |
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EMBL |
AB257502
AB259570
AB259571
AK040991
AK131154
AL731831
AL731836
BC113165
BC113776
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GenPept |
AAI13166
AAI13777
BAC30772
BAD21404
BAF03614
BAF03615
BAF03616
CAM13442
CAM13878
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