InnateDB Protein
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IDBP-204912.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Prom2
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Protein Name
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prominin 2
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000099503
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InnateDB Gene
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IDBG-204902 (Prom2)
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Protein Structure
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Function |
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Subcellular Localization |
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Cell projection, cilium membrane; Multi-pass membrane protein. Note=Colocalizes with PROM1 (By similarity). Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in kidney and testis. Present in urine within small membrane particles (at protein level). In the submandibular gland, expressed in seromucous acini. In the parotid gland, expressed in the serous acini and in all segments of the duct system. In the sublingual gland, expressed in large excretory ducts, but absent in intercalated ducts. In the extraorbital lacrimal gland, expressed in the serous acini. In the eyelid, expressed in the acini of the meibomian gland. {ECO:0000269PubMed:12514187, ECO:0000269PubMed:17109118, ECO:0000269PubMed:17874118}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2138997
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InterPro |
IPR008795
Prominin
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PFAM |
PF05478
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3UUY6
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PhosphoSite |
PhosphoSite-Q3UUY6
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
192212
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UniGene |
Mm.34171
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RefSeq |
NP_835148
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MGI ID |
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MGI Symbol |
Prom2
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OMIM |
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CCDS |
CCDS50704
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HPRD |
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IMGT |
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EMBL |
AF128113
AF269062
AK029851
AK137749
AL731831
BC039212
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GenPept |
AAD22488
AAH39212
AAM10543
BAC26644
BAE23487
CAM13444
CAM13445
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