InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nhlh1

Summary

InnateDB Protein

IDBP-204932.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nhlh1

Protein Name

nescient helix loop helix 1

Synonyms

bHLHa35; Hen1; Nscl; Tal2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000057489

InnateDB Gene

IDBG-204930 (Nhlh1)

Protein Structure

UniProt Annotation

Function

May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00981}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0046983	protein dimerization activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0030154	cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter