Version 5.4
Mus musculus Protein: Rrp8
Summary
InnateDB Protein IDBP-204938.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Rrp8
Protein Name ribosomal RNA processing 8, methyltransferase, homolog (yeast)
Synonyms 1500003O22Rik; 2900001K19Rik; AW538116;
Species Mus musculus
Ensembl Protein ENSMUSP00000095752
InnateDB Gene IDBG-204936 (Rrp8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008168 methyltransferase activity
GO:0035064 methylated histone binding
Biological Process
GO:0000183 chromatin silencing at rDNA
GO:0008152 metabolic process
GO:0032259 methylation
GO:0042149 cellular response to glucose starvation
GO:0046015 regulation of transcription by glucose
GO:0071158 positive regulation of cell cycle arrest
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
Cellular Component
GO:0005677 chromatin silencing complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0033553 rDNA heterochromatin
Protein Structure and Domains
PDB ID MGI:1914251
InterPro IPR007823 Methyltransferase-related
IPR013216 Methyltransferase type 11
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like
PFAM PF05148
PF08241
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PVA2
UniProt Splice Variant
Entrez Gene 101867
UniGene Mm.393272
RefSeq NP_598712
MGI ID
MGI Symbol Rrp8
OMIM
CCDS CCDS57576
HPRD
IMGT
EMBL AC121823
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca