InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Csrnp1

Summary

InnateDB Protein

IDBP-205002.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Csrnp1

Protein Name

cysteine-serine-rich nuclear protein 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035101

InnateDB Gene

IDBG-205000 (Csrnp1)

Protein Structure

UniProt Annotation

Function

Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May have a tumor-suppressor function. May play a role in apoptosis. {ECO:0000269PubMed:17726538}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:17726538}.

Disease Associations

Tissue Specificity

Widely expressed with highest levels in thymus and lung. Low levels detected in naive T-cells. {ECO:0000269PubMed:17726538}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006915	apoptotic process
GO:0009791	post-embryonic development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048008	platelet-derived growth factor receptor signaling pathway
GO:0048705	skeletal system morphogenesis
GO:0060021	palate development
GO:0060325	face morphogenesis