Version 5.4
Mus musculus Protein: Slc25a38
Summary
InnateDB Protein IDBP-205032.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc25a38
Protein Name solute carrier family 25, member 38
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000035106
InnateDB Gene IDBG-205030 (Slc25a38)
Protein Structure
UniProt Annotation
Function Mitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane. {ECO:0000255HAMAP- Rule:MF_03064}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000255HAMAP-Rule:MF_03064}; Multi-pass membrane protein {ECO:0000255HAMAP-Rule:MF_03064}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006810 transport
GO:0030218 erythrocyte differentiation
Cellular Component
GO:0005575 cellular_component
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2384782
InterPro IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00153
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91XD8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 208638
UniGene Mm.452117
RefSeq NP_659042
MGI ID
MGI Symbol Slc25a38
OMIM
CCDS CCDS23622
HPRD
IMGT
EMBL AK078385 BC010801
GenPept AAH10801 BAC37246

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca