Version 5.4
Mus musculus Protein: Dcaf8
Summary
InnateDB Protein IDBP-205203.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dcaf8
Protein Name DDB1 and CUL4 associated factor 8
Synonyms AA408877; AA433120; AA792214; AU018973; C76055; D1Dau35e; D1Ucla4; H326; Wdr42a;
Species Mus musculus
Ensembl Protein ENSMUSP00000073778
InnateDB Gene IDBG-205199 (Dcaf8)
Protein Structure
UniProt Annotation
Function May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in the brain. {ECO:0000269PubMed:11401431}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
Protein Structure and Domains
PDB ID MGI:91860
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N7N5
PhosphoSite PhosphoSite-Q8N7N5
TrEMBL
UniProt Splice Variant
Entrez Gene 98193
UniGene Mm.470423
RefSeq NP_705783
MGI ID
MGI Symbol Dcaf8
OMIM
CCDS CCDS15509
HPRD
IMGT
EMBL AK098114 AK146825 BC023704 BC023804
GenPept AAH23704 AAH23804 BAC05237 BAE27462

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca