InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mmp28

Summary

InnateDB Protein

IDBP-205376.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Mmp28

Protein Name

matrix metallopeptidase 28 (epilysin)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099498

InnateDB Gene

IDBG-205372 (Mmp28)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004222	metalloendopeptidase activity
GO:0005509	calcium ion binding
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0010760	negative regulation of macrophage chemotaxis

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005737	cytoplasm
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

MGI:2153062

InterPro

IPR000585 Hemopexin-like domain
IPR001818 Peptidase M10, metallopeptidase
IPR002477 Peptidoglycan binding-like
IPR006026 Peptidase, metallopeptidase
IPR016293 Peptidase M10A, stromelysin-type
IPR018487 Hemopexin-like repeats
IPR021190 Peptidase M10A

PFAM

PF00413
PF01471
PF00045

PRINTS

PR00138

PIRSF

PIRSF001191

SMART

SM00235
SM00120

TIGRFAMs

Post-translational Modifications

Modification

Cross-References