Version 5.4
Mus musculus Protein: Nyap1
Summary
InnateDB Protein IDBP-205396.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nyap1
Protein Name RIKEN cDNA 6430598A04 gene
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000058217
InnateDB Gene IDBG-205394 (Nyap1)
Protein Structure
UniProt Annotation
Function Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis. {ECO:0000269PubMed:21946561}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed predominantly in brain where it is present in the neurons, but not in astrocytes or oligodendrites. {ECO:0000269PubMed:21946561}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0048812 neuron projection morphogenesis
Cellular Component
Protein Structure and Domains
PDB ID MGI:2443880
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PFX7
PhosphoSite PhosphoSite-Q6PFX7
TrEMBL
UniProt Splice Variant
Entrez Gene 243300
UniGene Mm.74750
RefSeq XP_006504638
MGI ID
MGI Symbol Nyap1
OMIM
CCDS CCDS19775
HPRD
IMGT
EMBL AB429289 AK032567 AK080821 AK148980 BC057372 CH466529
GenPept AAH57372 BAC27928 BAC38036 BAE28710 BAJ19138 EDL19242

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca