InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vipr1

Summary

InnateDB Protein

IDBP-205463.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vipr1

Protein Name

vasoactive intestinal peptide receptor 1

Synonyms

AV071699; VIP-R1; VPAC1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035115

InnateDB Gene

IDBG-205461 (Vipr1)

Protein Structure

UniProt Annotation

Function

This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0004999	vasoactive intestinal polypeptide receptor activity
GO:0005515	protein binding

Biological Process

GO:0007166	cell surface receptor signaling pathway
GO:0007186	G-protein coupled receptor signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043235	receptor complex

Protein Structure and Domains

PDB ID

MGI:109272

InterPro

IPR000832 GPCR, family 2, secretin-like
IPR001571 GPCR, family 2, vasoactive intestinal peptide receptor
IPR001771 GPCR, family 2, vasoactive intestinal peptide receptor 1
IPR001879 GPCR, family 2, extracellular hormone receptor domain
IPR017981 GPCR, family 2-like

PFAM

PF00002
PF02793

PRINTS

PR00249
PR00491
PR01154

PIRSF

SMART

SM00008

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt