Version 5.4
Mus musculus Protein: Ccl9
Summary
InnateDB Protein IDBP-205531.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccl9
Protein Name chemokine (C-C motif) ligand 9
Synonyms CCF18; MRP-2; Scya10; Scya9;
Species Mus musculus
Ensembl Protein ENSMUSP00000019266
InnateDB Gene IDBG-205529 (Ccl9)
Protein Structure
UniProt Annotation
Function Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 1 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008009 chemokine activity
Biological Process
GO:0006955 immune response
GO:0060326 cell chemotaxis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:104533
InterPro IPR001811 Chemokine interleukin-8-like domain
PFAM PF00048
PRINTS
PIRSF
SMART SM00199
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51670
PhosphoSite PhosphoSite-
TrEMBL Q3U9T8
UniProt Splice Variant
Entrez Gene 20308
UniGene Mm.469185
RefSeq NP_035468
MGI ID
MGI Symbol Ccl9
OMIM
CCDS CCDS25170
HPRD
IMGT
EMBL AB051897 AF128195 AF128196 AF128197 AF128198 AF128199 AF128200 AF128201 AF128202 AF128203 AF128204 AK151131 AK151649 AK154511 AK155032 AK155036 AL596122 BC139318 BC145962 CH466556 U15209 U19482 U49513
GenPept AAA92583 AAB02198 AAB17120 AAF22536 AAF22537 AAF22538 AAF22539 AAF22540 AAF22541 AAF22542 AAF22543 AAF22544 AAF22545 AAI39319 AAI45963 BAB18730 BAE30139 BAE30578 BAE32640 BAE33004 BAE33005 CAI25133 EDL15711

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca