Version 5.4
Mus musculus Protein: Slc2a5
Summary
InnateDB Protein IDBP-205572.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc2a5
Protein Name solute carrier family 2 (facilitated glucose transporter), member 5
Synonyms AI526984; Glut5; Slc5a;
Species Mus musculus
Ensembl Protein ENSMUSP00000030826
InnateDB Gene IDBG-205570 (Slc2a5)
Protein Structure
UniProt Annotation
Function Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter (By similarity). {ECO:0000250}.
Subcellular Localization Apical cell membrane {ECO:0000269PubMed:18496516}; Multi-pass membrane protein {ECO:0000269PubMed:18496516}. Membrane {ECO:0000269PubMed:18496516}; Multi-pass membrane protein {ECO:0000269PubMed:18496516}. Note=Localized on the apical membrane of the small intestine and the proximal tubule of the kidney.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005353 fructose transmembrane transporter activity
GO:0005355 glucose transmembrane transporter activity
GO:0022857 transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity
Biological Process
GO:0015755 fructose transport
GO:0015758 glucose transport
GO:0055085 transmembrane transport
GO:0071332 cellular response to fructose stimulus
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1928369
InterPro IPR002442 Fructose transporter, type 5 (GLUT5)
IPR003663 Sugar/inositol transporter
IPR005828 General substrate transporter
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain
PFAM PF00083
PF07690
PRINTS PR01194
PR00171
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WV38
PhosphoSite PhosphoSite-Q9WV38
TrEMBL
UniProt Splice Variant
Entrez Gene 56485
UniGene Mm.260220
RefSeq NP_062715
MGI ID
MGI Symbol Slc2a5
OMIM
CCDS CCDS18968
HPRD
IMGT
EMBL AF161071 AK029720 AL606971 BC023500 CH466594 CU210939
GenPept AAD42235 AAH23500 BAC26582 CAM14288 CAQ51688 EDL14883

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca