Mus musculus Protein: Gjc3
Summary
InnateDB Protein IDBP-205616.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gjc3
Protein Name gap junction protein, gamma 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000076367
InnateDB Gene IDBG-205614 (Gjc3)
Protein Structure
UniProt Annotation
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}.
Disease Associations
Tissue Specificity CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005243 gap junction channel activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0007267 cell-cell signaling
GO:0007605 sensory perception of sound
GO:0042552 myelination
GO:0055085 transmembrane transport
Cellular Component
GO:0005921 gap junction
GO:0005922 connexon complex
GO:0016021 integral component of membrane
GO:0043209 myelin sheath
Protein Structure and Domains
PDB ID MGI:2153041
InterPro IPR000500 Connexin
IPR013092 Connexin, N-terminal
IPR019570 Gap junction protein, cysteine-rich domain
PFAM PF00029
PF10582
PRINTS PR00206
PIRSF
SMART SM00037
SM01089
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q921C1
PhosphoSite PhosphoSite-Q921C1
TrEMBL
UniProt Splice Variant
Entrez Gene 118446
UniGene Mm.475501
RefSeq NP_536698
MGI ID
MGI Symbol Gjc3
OMIM
CCDS CCDS19782
HPRD
IMGT
EMBL AF503616 AJ297318 AK034037 AK045577 AK047368 AK147913 AY289210 AY293564 AY297108 AY823670 BC125305 CH466529
GenPept AAI25306 AAM21146 AAP41202 AAP50246 AAP51160 AAX39497 BAC28554 BAC32421 BAC33038 BAE28224 CAC29245 EDL19225 EDL19226