InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Azgp1

Summary

InnateDB Protein

IDBP-205634.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Azgp1

Protein Name

alpha-2-glycoprotein 1, zinc

Synonyms

Zag;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000038559

InnateDB Gene

IDBG-205632 (Azgp1)

Protein Structure

UniProt Annotation

Function

Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. {ECO:0000250}.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0003823	antigen binding
GO:0005515	protein binding
GO:0042605	peptide antigen binding

Biological Process

GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
GO:0001895	retina homeostasis
GO:0001916	positive regulation of T cell mediated cytotoxicity
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
GO:0006955	immune response
GO:0007155	cell adhesion
GO:0019882	antigen processing and presentation
GO:0040014	regulation of multicellular organism growth

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0042612	MHC class I protein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:103163

InterPro

IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR011162 MHC classes I/II-like antigen recognition protein
IPR027648 MHC class I alpha chain

PFAM

PF00129
PF07654

PRINTS

PR01638

PIRSF

SMART

SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt