Version 5.4
Mus musculus Protein: Darc
Summary
InnateDB Protein IDBP-205830.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Darc
Protein Name Duffy blood group, chemokine receptor
Synonyms AA162249; CCBP1; CD234; Darc; Dfy; ESTM35; FY; GPD;
Species Mus musculus
Ensembl Protein ENSMUSP00000045134
InnateDB Gene IDBG-205828 (Darc)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0019957 C-C chemokine binding
Biological Process
GO:0006954 inflammatory response
GO:0007186 G-protein coupled receptor signaling pathway
GO:0032642 regulation of chemokine production
GO:0070098 chemokine-mediated signaling pathway
Cellular Component
GO:0005769 early endosome
GO:0016021 integral component of membrane
GO:0055037 recycling endosome
Protein Structure and Domains
PDB ID MGI:1097689
InterPro IPR005384 Duffy antigen/chemokine receptor
PFAM
PRINTS PR01559
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QUI6
PhosphoSite PhosphoSite-Q9QUI6
TrEMBL
UniProt Splice Variant
Entrez Gene 13349
UniGene Mm.6393
RefSeq NP_034175
MGI ID
MGI Symbol Ackr1
OMIM
CCDS CCDS35789
HPRD
IMGT
EMBL AB039074 AB039075 AB039076 AB039077 AB039078 AB039079 AB039080 AB039081 AB039082 AF016584 AF016697 AF109159 BC005583 U88431
GenPept AAC53354 AAC53360 AAF08328 AAF14225 AAH05583 BAB68598 BAB68599 BAB68600 BAB68601 BAB68602 BAB68603 BAB68604 BAB68605 BAB68606

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca