Version 5.4
Mus musculus Protein: Synrg
Summary
InnateDB Protein IDBP-205852.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Synrg
Protein Name synergin, gamma
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000090510
InnateDB Gene IDBG-205848 (Synrg)
Protein Structure
UniProt Annotation
Function May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000269PubMed:12808037}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269PubMed:12808037}; Peripheral membrane protein {ECO:0000269PubMed:12808037}. Note=Associated with membranes of the TGN, colocalizes with AP1G1 (By similarity). Associates with membranes via the adapter protein complex AP-1. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006897 endocytosis
GO:0008150 biological_process
GO:0015031 protein transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1354742
InterPro IPR000261 EPS15 homology (EH)
PFAM
PRINTS
PIRSF
SMART SM00027
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SV85
PhosphoSite PhosphoSite-Q5SV85
TrEMBL
UniProt Splice Variant
Entrez Gene 217030
UniGene Mm.82680
RefSeq NP_919322
MGI ID
MGI Symbol Synrg
OMIM
CCDS CCDS25181
HPRD
IMGT
EMBL AL645615 BC056370
GenPept AAH56370 CAI25509 CAI25510 CAI25511

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca