Mus musculus Protein: Mnda
Summary
InnateDB Protein IDBP-205999.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mnda
Protein Name myeloid cell nuclear differentiation antigen
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000009340
InnateDB Gene IDBG-205997 (Mnda)
Protein Structure
UniProt Annotation
Function May act as a transcriptional regulator in the myeloid lineage. Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways. {ECO:0000269PubMed:15342947, ECO:0000269PubMed:16458891}.
Subcellular Localization Nucleus {ECO:0000269PubMed:15342947}.
Disease Associations
Tissue Specificity Mononuclear phagocytes. {ECO:0000269PubMed:7684766}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:3041120
InterPro IPR004020 DAPIN domain
IPR004021 HIN-200/IF120x
IPR011029 Death-like domain
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF02758
PF02760
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q08619
PhosphoSite PhosphoSite-Q08619
TrEMBL B7ZNS3
UniProt Splice Variant
Entrez Gene 381308
UniGene Mm.490248
RefSeq NP_001028622
MGI ID 2YU0
MGI Symbol Mnda
OMIM
CCDS CCDS15532
HPRD
IMGT
EMBL AK080485 AK150522 AK152621 AK152683 AK152786 AK166217 BC132314 BC132316 BC145397 S62227
GenPept AAB26880 AAI32315 AAI32317 AAI45398 BAC37930 BAE29634 BAE31364 BAE31415 BAE31495 BAE38635