Mus musculus Protein: Ifi205
Summary
InnateDB Protein IDBP-206088.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ifi205
Protein Name interferon activated gene 205
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000062409
InnateDB Gene IDBG-206086 (Ifi205)
Protein Structure
UniProt Annotation
Function May act as a transcriptional regulator in the myeloid lineage. Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003690 double-stranded DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0035458 cellular response to interferon-beta
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:101847
InterPro IPR004020 DAPIN domain
IPR004021 HIN-200/IF120x
IPR011029 Death-like domain
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF02758
PF02760
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CGE8
PhosphoSite PhosphoSite-Q8CGE8
TrEMBL
UniProt Splice Variant
Entrez Gene 226695
UniGene
RefSeq NP_766236
MGI ID
MGI Symbol Ifi205
OMIM
CCDS CCDS15534
HPRD
IMGT
EMBL AK040191 BC040425 CT010211
GenPept AAH40425 BAC30535 CAJ18419