Version 5.4
| Mus musculus Protein: Tgm4 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-206147.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Tgm4 | ||||||||||
| Protein Name | transglutaminase 4 (prostate) | ||||||||||
| Synonyms | |||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Protein | ENSMUSP00000026893 | ||||||||||
| InnateDB Gene | IDBG-206145 (Tgm4) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Associated with the mammalian reproductive process. Plays an important role in the formation of the seminal coagulum through the cross-linking of specific proteins present in the seminal plasma. Transglutaminase is also required to stabilize the copulatory plug. {ECO:0000269PubMed:19027372}. | ||||||||||
| Subcellular Localization | Secreted {ECO:0000269PubMed:19027372}. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | Expressed in the coagulating gland and in the dorsal part of the prostate. Not expressed in the brain, heart, kidney, liver, lung, muscle, pancreas, spleen, stomach, testis and thymus. {ECO:0000269PubMed:16223778, ECO:0000269PubMed:19027372}. | ||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | MGI:3027002 | ||||||||||
| InterPro |
IPR001102
Transglutaminase, N-terminal IPR002931 Transglutaminase-like IPR008958 Transglutaminase, C-terminal IPR014756 Immunoglobulin E-set |
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| PFAM |
PF00868
PF01841 PF00927 |
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| PRINTS | |||||||||||
| PIRSF | |||||||||||
| SMART |
SM00460
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| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q8BZH1 | ||||||||||
| PhosphoSite | PhosphoSite-Q8BZH1 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 331046 | ||||||||||
| UniGene | Mm.195309 | ||||||||||
| RefSeq | NP_808579 | ||||||||||
| MGI ID | |||||||||||
| MGI Symbol | Tgm4 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS23653 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AF486627 AK035279 BC141297 BC145622 | ||||||||||
| GenPept | AAI41298 AAI45623 AAM45940 BAC29013 | ||||||||||