InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Thap3

Summary

InnateDB Protein

IDBP-206153.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Thap3

Protein Name

THAP domain containing, apoptosis associated protein 3

Synonyms

2010013E08Rik; 2210418H06Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035240

InnateDB Gene

IDBG-206151 (Thap3)

Protein Structure

UniProt Annotation

Function

Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Highest levels in heart, liver and kidney. Lower levels in brain and lung. {ECO:0000269PubMed:20200153}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:1917126

InterPro

IPR006612 Zinc finger, C2CH-type

PFAM

PF05485

PRINTS

PIRSF

SMART

SM00692
SM00980

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BJ25

PhosphoSite

PhosphoSite-

TrEMBL

Q52KE1

UniProt Splice Variant

Entrez Gene

69876

UniGene

RefSeq

NP_780361

MGI ID

MGI Symbol

Thap3

OMIM

CCDS

CCDS18982

HPRD

IMGT

EMBL

AK038184 AK050740 BC094395 CH466594

GenPept

AAH94395 BAC29945 BAC34401 EDL14913