InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cdcp1

Summary

InnateDB Protein

IDBP-206227.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cdcp1

Protein Name

CUB domain containing protein 1

Synonyms

9030022E12Rik; AA409659; E030027H19Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000042057

InnateDB Gene

IDBG-206225 (Cdcp1)

Protein Structure

UniProt Annotation

Function

May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.

Subcellular Localization

Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Its shedding may lead to a soluble peptide. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2442010

InterPro

IPR000859 CUB domain

PFAM

PF00431

PRINTS

PIRSF

SMART

SM00042

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5U462

PhosphoSite

PhosphoSite-Q5U462

TrEMBL

UniProt Splice Variant

Entrez Gene

109332

UniGene

Mm.27519

RefSeq

NP_598735

MGI ID

MGI Symbol

Cdcp1

OMIM

CCDS

CCDS23657

HPRD

IMGT

EMBL

BC011340 BC050137 BC085253

GenPept

AAH11340 AAH50137 AAH85253