InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mrm1

Summary

InnateDB Protein

IDBP-206320.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mrm1

Protein Name

mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000018549

InnateDB Gene

IDBG-206318 (Mrm1)

Protein Structure

UniProt Annotation

Function

Probably methylates the ribose of guanosine G-2270 in the peptidyl transferase center of the mitochondrial large ribosomal RNA (21S). {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0008168	methyltransferase activity
GO:0008173	RNA methyltransferase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001510	RNA methylation
GO:0006396	RNA processing
GO:0008150	biological_process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

MGI:2443470

InterPro

IPR001537 tRNA/rRNA methyltransferase, SpoU type
IPR013123 RNA 2-O ribose methyltransferase, substrate binding
IPR029028 Alpha/beta knot methyltransferases
IPR029064 50S ribosomal protein L30e-like

PFAM

PF00588
PF08032

PRINTS

PIRSF

SMART

SM00967

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99J25