Version 5.4
Mus musculus Protein: Tmem41b
Summary
InnateDB Protein IDBP-206382.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem41b
Protein Name transmembrane protein 41B
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000091641
InnateDB Gene IDBG-206380 (Tmem41b)
Protein Structure
UniProt Annotation
Function Required for normal motor neuron development. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in brain, spinal cord, kidney and first lumbar dorsal root ganglia during postnatal development. Expressed in motor neurons and proprioceptive neurons. {ECO:0000269PubMed:23063131}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007399 nervous system development
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1289225
InterPro IPR015414 SNARE associated Golgi protein
PFAM PF09335
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K1A5
PhosphoSite PhosphoSite-Q8K1A5
TrEMBL D6RFP3
UniProt Splice Variant
Entrez Gene 233724
UniGene Mm.488869
RefSeq NP_705745
MGI ID
MGI Symbol Tmem41b
OMIM
CCDS CCDS21742
HPRD
IMGT
EMBL AC140235 AK029327 AK033997 AK035266 AK035365 AK038953 AK078357 AK090100 AK139961 AK150353 AK153048 AK165226 AK166427 AK166455 AK166845 AK172876 BC026515 BC027103
GenPept AAH26515 AAH27103 BAC26397 BAC28541 BAC29008 BAC29048 BAC30179 BAC37235 BAC41091 BAD32154 BAE24197 BAE29490 BAE31676 BAE38087 BAE38770 BAE38786 BAE39064

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca