Version 5.4
Mus musculus Protein: Myo19
Summary
InnateDB Protein IDBP-206432.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myo19
Protein Name myosin XIX
Synonyms 1110055A02Rik; Myohd1;
Species Mus musculus
Ensembl Protein ENSMUSP00000091502
InnateDB Gene IDBG-206428 (Myo19)
Protein Structure
UniProt Annotation
Function Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton. Mitochondrion outer membrane. Note=Probably associated with the outer membrane via its N-terminal mitochondrial targeting region. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003774 motor activity
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005741 mitochondrial outer membrane
GO:0016459 myosin complex
Protein Structure and Domains
PDB ID MGI:1913446
InterPro IPR000048 IQ motif, EF-hand binding site
IPR001609 Myosin head, motor domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00612
PF00063
PRINTS PR00193
PIRSF
SMART SM00015
SM00242
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SV80
PhosphoSite PhosphoSite-Q5SV80
TrEMBL
UniProt Splice Variant
Entrez Gene 66196
UniGene Mm.288689
RefSeq NP_079690
MGI ID
MGI Symbol Myo19
OMIM
CCDS CCDS48871
HPRD
IMGT
EMBL AK018609 AK053033 AK053237 AL645623 BC007156
GenPept AAH07156 BAB31305 BAC35243 BAC35317 CAI25489 CAI25490

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca