InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cxcr6

Summary

InnateDB Protein

IDBP-206492.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cxcr6

Protein Name

chemokine (C-X-C motif) receptor 6

Synonyms

BB217514; BONZO; STRL33;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000060776

InnateDB Gene

IDBG-206490 (Cxcr6)

Protein Structure

UniProt Annotation

Function

Receptor for the C-X-C chemokine CXCL16. {ECO:0000269PubMed:11017100}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0015026	coreceptor activity
GO:0016494	C-X-C chemokine receptor activity

Biological Process

GO:0006935	chemotaxis
GO:0006954	inflammatory response
GO:0007186	G-protein coupled receptor signaling pathway
GO:0045087	innate immune response (InnateDB)
GO:0070098	chemokine-mediated signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1934582

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000355 Chemokine receptor family
IPR001277 CXC chemokine receptor 4
IPR002235 CXC chemokine receptor 6
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00237
PR00657
PR00645
PR01105

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9EQ16