InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ccr1l1

Summary

InnateDB Protein

IDBP-206543.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ccr1l1

Protein Name

chemokine (C-C motif) receptor 1-like 1

Synonyms

Cmkbr1l1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000071353

InnateDB Gene

IDBG-206541 (Ccr1l1)

Protein Structure

UniProt Annotation

Function

Probable receptor for a C-C type chemokine.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Detected in the spleen, liver and leukocytes.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0016493	C-C chemokine receptor activity

Biological Process

GO:0006935	chemotaxis
GO:0006954	inflammatory response
GO:0006955	immune response
GO:0007186	G-protein coupled receptor signaling pathway
GO:0070098	chemokine-mediated signaling pathway
GO:0090026	positive regulation of monocyte chemotaxis

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:104617

InterPro

IPR000248 Angiotensin II receptor family
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000355 Chemokine receptor family
IPR002236 CC chemokine receptor 1
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00241
PR00237
PR00657
PR01106

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P51676