Version 5.4
Mus musculus Protein: Appbp2
Summary
InnateDB Protein IDBP-206586.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Appbp2
Protein Name amyloid beta precursor protein (cytoplasmic tail) binding protein 2
Synonyms 1300003O07Rik; AI465480; PAT1;
Species Mus musculus
Ensembl Protein ENSMUSP00000018625
InnateDB Gene IDBG-206584 (Appbp2)
Protein Structure
UniProt Annotation
Function May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Associated with membranes and microtubules. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0046907 intracellular transport
Cellular Component
GO:0005634 nucleus
GO:0005874 microtubule
GO:0030659 cytoplasmic vesicle membrane
Protein Structure and Domains
PDB ID MGI:1914134
InterPro IPR013026 Tetratricopeptide repeat-containing domain
IPR019734 Tetratricopeptide repeat
PFAM PF13174
PF13176
PF13181
PRINTS
PIRSF
SMART SM00028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DAX9
PhosphoSite PhosphoSite-Q9DAX9
TrEMBL
UniProt Splice Variant
Entrez Gene 66884
UniGene Mm.479498
RefSeq NP_080101
MGI ID
MGI Symbol Appbp2
OMIM
CCDS CCDS25193
HPRD
IMGT
EMBL AK005440 AK122222 AL596183 BC018442 BC019152
GenPept AAH18442 AAH19152 BAB24034 BAC65504 CAI24920

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca