InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Micall2

Summary

InnateDB Protein

IDBP-206697.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Micall2

Protein Name

MICAL-like 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000039707

InnateDB Gene

IDBG-206695 (Micall2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0017137	Rab GTPase binding
GO:0031005	filamin binding
GO:0042805	actinin binding
GO:0051015	actin filament binding

Biological Process

GO:0030041	actin filament polymerization
GO:0031175	neuron projection development
GO:0031532	actin cytoskeleton reorganization
GO:0032456	endocytic recycling
GO:0034446	substrate adhesion-dependent cell spreading
GO:0070830	tight junction assembly

Cellular Component

GO:0001725	stress fiber
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0005923	tight junction
GO:0032432	actin filament bundle
GO:0043005	neuron projection
GO:0055037	recycling endosome

Protein Structure and Domains

PDB ID

MGI:2444818

InterPro

IPR001715 Calponin homology domain
IPR001781 Zinc finger, LIM-type
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain
IPR022735 Domain of unknown function DUF3585

PFAM

PF00307
PF00412
PF11971
PF12130

PRINTS

PIRSF

SMART

SM00033
SM00132

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3TN34