Version 5.4
Mus musculus Protein: Sdccag8
Summary
InnateDB Protein IDBP-206700.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sdccag8
Protein Name serologically defined colon cancer antigen 8
Synonyms 2700048G21Rik; 5730470G24Rik; Cccap;
Species Mus musculus
Ensembl Protein ENSMUSP00000027785
InnateDB Gene IDBG-206698 (Sdccag8)
Protein Structure
UniProt Annotation
Function Plays a role in the establishment of cell polarity and epithelial lumen formation. May play a role in ciliogenesis. {ECO:0000269PubMed:20835237}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269PubMed:12559564, ECO:0000269PubMed:20835237}. Cell junction {ECO:0000250}. Note=Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle. Pariculary prominent at the distal basal body and the transition zone of photoreceptors.
Disease Associations
Tissue Specificity Expressed in liver, kidney, spleen, brain, heart and muscle. Expressed in photoreceptor cells of the retina. {ECO:0000269PubMed:12559564, ECO:0000269PubMed:20835237}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0030010 establishment of cell polarity
GO:0035148 tube formation
Cellular Component
GO:0005813 centrosome
GO:0005814 centriole
GO:0005911 cell-cell junction
Protein Structure and Domains
PDB ID MGI:1924066
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80UF4
PhosphoSite PhosphoSite-
TrEMBL Q9CYH0
UniProt Splice Variant
Entrez Gene 76816
UniGene Mm.171399
RefSeq NP_084032
MGI ID
MGI Symbol Sdccag8
OMIM
CCDS CCDS35798
HPRD
IMGT
EMBL AF250729 AK017691 AK132316 AK133622
GenPept AAO27828 BAB30877 BAE21100 BAE21753

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca