InnateDB Protein
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IDBP-206724.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ints1
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Protein Name
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integrator complex subunit 1
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Synonyms
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1110015K06Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000072406
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InnateDB Gene
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IDBG-206722 (Ints1)
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Protein Structure
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Function |
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
Experimentally validated |
Total |
7
[view]
|
Protein-Protein |
6
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
36 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1915760
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InterPro |
IPR016024
Armadillo-type fold
IPR022145
Protein of unknown function DUF3677
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PFAM |
PF12432
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q6P4S8
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PhosphoSite |
PhosphoSite-Q6P4S8
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TrEMBL |
Q3U1N8
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UniProt Splice Variant |
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Entrez Gene |
68510
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UniGene |
Mm.292942
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RefSeq |
NP_081024
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MGI ID |
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MGI Symbol |
Ints1
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OMIM |
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CCDS |
CCDS57399
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HPRD |
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IMGT |
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EMBL |
AB257854
AB257859
AC167333
AK003728
AK155838
BC010333
BC063266
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GenPept |
AAH10333
AAH63266
BAB22963
BAE33457
BAF03197
BAF03202
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