InnateDB Protein
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IDBP-206769.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Adss
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Protein Name
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adenylosuccinate synthetase, non muscle
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Synonyms
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Adss2; AI314886; AS;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000016105
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InnateDB Gene
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IDBG-206767 (Adss)
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Protein Structure
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|
Function |
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. {ECO:0000269PubMed:12482871}.
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Subcellular Localization |
Cytoplasm.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
7 [view]
|
|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:87948
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InterPro |
IPR001114
Adenylosuccinate synthetase
IPR027417
P-loop containing nucleoside triphosphate hydrolase
|
PFAM |
PF00709
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PRINTS |
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PIRSF |
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SMART |
SM00788
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TIGRFAMs |
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Modification |
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SwissProt |
P46664
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PhosphoSite |
PhosphoSite-P46664
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TrEMBL |
B9EIE9
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UniProt Splice Variant |
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Entrez Gene |
11566
|
UniGene |
Mm.470004
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RefSeq |
NP_031448
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MGI ID |
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MGI Symbol |
Adss
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OMIM |
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CCDS |
CCDS15555
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HPRD |
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IMGT |
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EMBL |
AK004877
AK010263
AK028060
AK148420
AK170279
BC139404
BC139417
CH466555
L24554
|
GenPept |
AAA19727
AAI39405
AAI39418
BAB23635
BAB26805
BAC25730
BAE28543
BAE41682
EDL13189
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