InnateDB Protein
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IDBP-206923.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cnst
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Protein Name
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consortin, connexin sorting protein
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000048205
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InnateDB Gene
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IDBG-206921 (Cnst)
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Protein Structure
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Function |
Required for targeting of connexins to the plasma membrane. {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Note=Located predominantly in the trans-Golgi network. Probably trafficks between the trans-Golgi network and the cell membrane via the secretory pathway (By similarity). {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
10 [view]
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Molecular Function |
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Biological Process |
GO:0010923
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negative regulation of phosphatase activity
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GO:0042998
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positive regulation of Golgi to plasma membrane protein transport
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Cellular Component |
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PDB ID |
MGI:2445141
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8CBC4
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PhosphoSite |
PhosphoSite-Q8CBC4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
226744
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UniGene |
Mm.87662
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RefSeq |
NP_666217
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MGI ID |
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MGI Symbol |
Cnst
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OMIM |
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CCDS |
CCDS15562
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HPRD |
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IMGT |
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EMBL |
AK036332
AK040666
AK040899
AK146681
BC034107
BC054802
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GenPept |
AAH34107
AAH54802
BAC29388
BAC30660
BAC30736
BAE27356
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