Mus musculus Protein: Lefty2
Summary
InnateDB Protein IDBP-207347.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lefty2
Protein Name left-right determination factor 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000082952
InnateDB Gene IDBG-207345 (Lefty2)
Protein Structure
UniProt Annotation
Function Required for left-right asymmetry determination of organ systems in mammals.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 0
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005160 transforming growth factor beta receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0007275 multicellular organismal development
GO:0016049 cell growth
GO:0040007 growth
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:2443573
InterPro IPR001111 Transforming growth factor-beta, N-terminal
IPR001839 Transforming growth factor-beta, C-terminal
IPR003942 Left- Right determination factor
IPR029034 Cystine-knot cytokine
PFAM PF00688
PF00019
PRINTS PR01427
PIRSF PIRSF037402
SMART SM00204
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P57785
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 320202
UniGene Mm.87078
RefSeq NP_796073
MGI ID
MGI Symbol Lefty2
OMIM
CCDS CCDS15575
HPRD
IMGT
EMBL AK031621 BC066224
GenPept AAH66224 BAC27483