InnateDB Protein
|
IDBP-207661.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Srp9
|
Protein Name
|
signal recognition particle 9
|
Synonyms
|
9kDa;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000027792
|
InnateDB Gene
|
IDBG-207659 (Srp9)
|
Protein Structure
|
|
Function |
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
|
Subcellular Localization |
Cytoplasm.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
20 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0006614
|
SRP-dependent cotranslational protein targeting to membrane
|
GO:0045900
|
negative regulation of translational elongation
|
|
Cellular Component |
GO:0005786
|
signal recognition particle, endoplasmic reticulum targeting
|
GO:0048500
|
signal recognition particle
|
GO:0070062
|
extracellular vesicular exosome
|
|
PDB ID |
MGI:1350930
|
InterPro |
IPR008832
Signal recognition particle, SRP9 subunit
IPR009018
Signal recognition particle, SRP9/SRP14 subunit
|
PFAM |
|
PRINTS |
|
PIRSF |
PIRSF017029
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P49962
|
PhosphoSite |
PhosphoSite-P49962
|
TrEMBL |
Q5EAT0
|
UniProt Splice Variant |
|
Entrez Gene |
27058
|
UniGene |
Mm.482409
|
RefSeq |
NP_036188
|
MGI ID |
1914
|
MGI Symbol |
Srp9
|
OMIM |
|
CCDS |
CCDS35812
|
HPRD |
|
IMGT |
|
EMBL |
AK011720
AK020583
AK020620
AK051208
AK169314
BC039648
BC090254
CH466555
X78304
|
GenPept |
AAH39648
AAH90254
BAB27800
BAB32138
BAB32151
BAC34557
BAE41069
CAA55114
EDL13112
|
|
|