InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Acsm2

Summary

InnateDB Protein

IDBP-207992.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Acsm2

Protein Name

acyl-CoA synthetase medium-chain family member 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000095690

InnateDB Gene

IDBG-207990 (Acsm2)

Protein Structure

UniProt Annotation

Function

Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005524	ATP binding
GO:0046872	metal ion binding
GO:0047760	butyrate-CoA ligase activity

Biological Process

GO:0006631	fatty acid metabolic process
GO:0008152	metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

MGI:2385289

InterPro

IPR000873 AMP-dependent synthetase/ligase

PFAM

PF00501

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K0L3

PhosphoSite

PhosphoSite-Q8K0L3

TrEMBL

Q8R1K7

UniProt Splice Variant

Entrez Gene

233799

UniGene

Mm.394671

RefSeq

NP_001171448

MGI ID

MGI Symbol

Acsm2

OMIM

CCDS

CCDS52379

HPRD

IMGT

EMBL

AK057650 AK140827 AK143757 AK165353 AK165401 BC024424 BC024450 BC031140

GenPept

AAH24424 AAH24450 AAH31140 BAB71542 BAE24490 BAE25526 BAE38146 BAE38163