InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Acsm4

Summary

InnateDB Protein

IDBP-208056.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Acsm4

Protein Name

acyl-CoA synthetase medium-chain family member 4

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000045160

InnateDB Gene

IDBG-208054 (Acsm4)

Protein Structure

UniProt Annotation

Function

Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004321	fatty-acyl-CoA synthase activity
GO:0005524	ATP binding
GO:0046872	metal ion binding
GO:0047760	butyrate-CoA ligase activity

Biological Process

GO:0006631	fatty acid metabolic process
GO:0006637	acyl-CoA metabolic process
GO:0008152	metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

MGI:2681844

InterPro

IPR000873 AMP-dependent synthetase/ligase

PFAM

PF00501

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

MGI ID

MGI Symbol

OMIM

CCDS

HPRD

IMGT

EMBL

AK132127 BC048390

GenPept

AAH48390 BAE20992

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca