InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ndufaf5

Summary

InnateDB Protein

IDBP-208124.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufaf5

Protein Name

RIKEN cDNA 2310003L22 gene

Synonyms

2310003L22Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035325

InnateDB Gene

IDBG-208122 (Ndufaf5)

Protein Structure

UniProt Annotation

Function

Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. May have methyltransferase activity (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}. Note=Peripherally localized on the matrix face of the mitochondrial inner membrane. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0008168	methyltransferase activity

Biological Process

GO:0008152	metabolic process
GO:0032259	methylation
GO:0032981	mitochondrial respiratory chain complex I assembly

Cellular Component

GO:0005739	mitochondrion
GO:0031314	extrinsic component of mitochondrial inner membrane

Protein Structure and Domains

PDB ID

MGI:1916737

InterPro

IPR004033 UbiE/COQ5 methyltransferase
IPR004159 Putative S-adenosyl-L-methionine-dependent methyltransferase
IPR013216 Methyltransferase type 11
IPR013217 Methyltransferase type 12
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF01209
PF03141
PF08241
PF08242

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A2APY7

PhosphoSite