Version 5.4
Mus musculus Protein: B3galt6
Summary
InnateDB Protein IDBP-208199.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B3galt6
Protein Name UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000057521
InnateDB Gene IDBG-208197 (B3galt6)
Protein Structure
UniProt Annotation
Function Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. Has no activity towards substrates with terminal glucosamine or galactosamine residues (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008378 galactosyltransferase activity
GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
GO:0035250 UDP-galactosyltransferase activity
GO:0047220 galactosylxylosylprotein 3-beta-galactosyltransferase activity
Biological Process
GO:0006024 glycosaminoglycan biosynthetic process
GO:0006486 protein glycosylation
GO:0015012 heparan sulfate proteoglycan biosynthetic process
GO:0030206 chondroitin sulfate biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005797 Golgi medial cisterna
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2152819
InterPro IPR002659 Glycosyl transferase, family 31
PFAM PF01762
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91Z92
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 117592
UniGene Mm.412880
RefSeq NP_536693
MGI ID
MGI Symbol B3galt6
OMIM
CCDS CCDS19053
HPRD
IMGT
EMBL AK033608 AK078083 AK090344 AY050569 BC082998
GenPept AAH82998 AAL11441 BAC28387 BAC37119 BAC41178

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca