InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cox11

Summary

InnateDB Protein

IDBP-208384.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cox11

Protein Name

COX11 homolog, cytochrome c oxidase assembly protein (yeast)

Synonyms

2010004I09Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020851

InnateDB Gene

IDBG-208382 (Cox11)

Protein Structure

UniProt Annotation

Function

Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005507	copper ion binding
GO:0005515	protein binding

Biological Process

GO:0033132

negative regulation of glucokinase activity

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1917052

InterPro

IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11
IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain

PFAM

PF04442

PRINTS

PIRSF

PIRSF005413

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6P8I6

PhosphoSite

PhosphoSite-

TrEMBL

Q5SRC5

UniProt Splice Variant

Entrez Gene

69802

UniGene

RefSeq

NP_950173

MGI ID

MGI Symbol

Cox11

OMIM

CCDS

CCDS25243

HPRD

IMGT

EMBL

AK143937 AL646046 AL672199 BC061233

GenPept

AAH61233 BAE25618 CAI23913 CAI24239