InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kif2b

Summary

InnateDB Protein

IDBP-208420.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kif2b

Protein Name

kinesin family member 2B

Synonyms

1700063D03Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000058084

InnateDB Gene

IDBG-208418 (Kif2b)

Protein Structure

UniProt Annotation

Function

Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Association with kinetochore is transient. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003777	microtubule motor activity
GO:0005524	ATP binding
GO:0008017	microtubule binding

Biological Process

GO:0007018	microtubule-based movement
GO:0007019	microtubule depolymerization
GO:0007067	mitotic nuclear division
GO:0008152	metabolic process
GO:0051983	regulation of chromosome segregation

Cellular Component

GO:0000777	condensed chromosome kinetochore
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005815	microtubule organizing center
GO:0005819	spindle
GO:0005871	kinesin complex
GO:0005874	microtubule
GO:0015630	microtubule cytoskeleton