InnateDB Protein
|
IDBP-208482.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Mbtd1
|
Protein Name
|
mbt domain containing 1
|
Synonyms
|
AA408199; AI194990; hemp;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000065442
|
InnateDB Gene
|
IDBG-208480 (Mbtd1)
|
Protein Structure
|
|
Function |
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4 (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Nucleus {ECO:0000305}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
3
[view]
|
Protein-DNA |
0
|
Protein-RNA |
1
[view]
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
6 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:2143977
|
InterPro |
IPR004092
Mbt repeat
IPR012313
Zinc finger, FCS-type
|
PFAM |
PF02820
|
PRINTS |
|
PIRSF |
|
SMART |
SM00561
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q6P5G3
|
PhosphoSite |
PhosphoSite-Q6P5G3
|
TrEMBL |
Q5NC76
|
UniProt Splice Variant |
|
Entrez Gene |
103537
|
UniGene |
Mm.472177
|
RefSeq |
XP_006531947
|
MGI ID |
|
MGI Symbol |
Mbtd1
|
OMIM |
|
CCDS |
|
HPRD |
|
IMGT |
|
EMBL |
AL662838
AL663078
BC020018
BC062907
BC064014
|
GenPept |
AAH20018
AAH62907
AAH64014
CAI25711
CAI25714
CAI35368
CAI35371
|
|
|