Version 5.4
Mus musculus Protein: Nme1
Summary
InnateDB Protein IDBP-208567.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nme1
Protein Name non-metastatic cells 1, protein (NM23A) expressed in
Synonyms AL024257; NDPK-A; NM23-M1; NM23A;
Species Mus musculus
Ensembl Protein ENSMUSP00000021220
InnateDB Gene IDBG-208565 (Nme1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 35 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003697 single-stranded DNA binding
GO:0004536 deoxyribonuclease activity
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0019215 intermediate filament binding
GO:0019901 protein kinase binding
GO:0042802 identical protein binding
GO:0043015 gamma-tubulin binding
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0002762 negative regulation of myeloid leukocyte differentiation
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0006308 DNA catabolic process
GO:0007595 lactation
GO:0010629 negative regulation of gene expression
GO:0010976 positive regulation of neuron projection development
GO:0014075 response to amine
GO:0021766 hippocampus development
GO:0030879 mammary gland development
GO:0033574 response to testosterone
GO:0035690 cellular response to drug
GO:0043388 positive regulation of DNA binding
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051591 response to cAMP
GO:0071333 cellular response to glucose stimulus
GO:0071398 cellular response to fatty acid
Cellular Component
GO:0005739 mitochondrion
GO:0005813 centrosome
GO:0005829 cytosol
GO:0032587 ruffle membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:97355
InterPro IPR001564 Nucleoside diphosphate kinase
PFAM PF00334
PRINTS PR01243
PIRSF
SMART SM00562
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5NC80
UniProt Splice Variant
Entrez Gene 18102
UniGene
RefSeq
MGI ID
MGI Symbol Nme1
OMIM
CCDS
HPRD
IMGT
EMBL AL662838
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca