|
InnateDB Protein
|
IDBP-208883.6
|
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
|
Gene Symbol
|
Nkx2-4
|
|
Protein Name
|
NK2 transcription factor related, locus 4 (Drosophila)
|
|
Synonyms
|
|
|
Species
|
Mus musculus
|
|
Ensembl Protein
|
ENSMUSP00000066690
|
|
InnateDB Gene
|
IDBG-208881 (Nkx2-4)
|
|
Protein Structure
|
|
| Function |
Probable transcription factor.
|
| Subcellular Localization |
Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.
|
| Disease Associations |
|
| Tissue Specificity |
In the embryo it is detected in the posterior hypotalamus and later in the head. In the adult it is detected only in testis.
|
| Comments |
|
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
1
[view]
|
| Protein-Protein |
1
[view]
|
| Protein-DNA |
0
|
| Protein-RNA |
0
|
| DNA-DNA |
0
|
| RNA-RNA |
0
|
| DNA-RNA |
0
|
|
|
|
Molecular Function |
| Accession |
GO Term |
|
GO:0003677
|
DNA binding
|
|
GO:0003700
|
sequence-specific DNA binding transcription factor activity
|
|
GO:0043565
|
sequence-specific DNA binding
|
|
| Biological Process |
|
GO:0006355
|
regulation of transcription, DNA-templated
|
|
GO:0007275
|
multicellular organismal development
|
|
| Cellular Component |
|
| PDB ID |
MGI:97349
|
| InterPro |
IPR001356
Homeobox domain
IPR009057
Homeodomain-like
IPR020479
Homeodomain, metazoa
|
| PFAM |
PF00046
|
| PRINTS |
PR00024
|
| PIRSF |
|
| SMART |
SM00389
|
| TIGRFAMs |
|
| Modification |
|
| SwissProt |
Q9EQM3
|
| PhosphoSite |
PhosphoSite-
|
| TrEMBL |
Q9CW04
|
| UniProt Splice Variant |
|
| Entrez Gene |
228731
|
| UniGene |
Mm.315498
|
| RefSeq |
NP_075993
|
| MGI ID |
|
| MGI Symbol |
Nkx2-4
|
| OMIM |
|
| CCDS |
CCDS16833
|
| HPRD |
|
| IMGT |
|
| EMBL |
AF202038
AF202039
AK005620
AL928876
|
| GenPept |
AAG35618
AAG35619
BAB24155
CAM18290
|
|
|
|
Version 5.4