Mus musculus Protein: Mtif3
Summary
InnateDB Protein IDBP-208953.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtif3
Protein Name mitochondrial translational initiation factor 3
Synonyms 2810012L14Rik; AI414549;
Species Mus musculus
Ensembl Protein ENSMUSP00000063398
InnateDB Gene IDBG-208951 (Mtif3)
Protein Structure
UniProt Annotation
Function IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0008135 translation factor activity, nucleic acid binding
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0001732 formation of translation initiation complex
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
GO:0032790 ribosome disassembly
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:1923616
InterPro IPR001288 Translation initiation factor 3
IPR019814 Translation initiation factor 3, N-terminal
IPR019815 Translation initiation factor 3, C-terminal
PFAM PF05198
PF00707
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CZD5
PhosphoSite PhosphoSite-
TrEMBL D3Z0H9
UniProt Splice Variant
Entrez Gene 76366
UniGene Mm.486234
RefSeq NP_083857
MGI ID 2CRQ
MGI Symbol Mtif3
OMIM
CCDS CCDS19874
HPRD
IMGT
EMBL AC124828 AK012733 AK147090 AL513345 BC052439 BC115684 BC115685 CH466614
GenPept AAH52439 AAI15685 AAI15686 BAB28438 BAE27670 EDL05823