InnateDB Protein
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IDBP-209000.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cacng3
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Protein Name
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calcium channel, voltage-dependent, gamma subunit 3
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000081664
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InnateDB Gene
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IDBG-208998 (Cacng3)
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Protein Structure
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Function |
Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). {ECO:0000250}.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
GO:0070588
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calcium ion transmembrane transport
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GO:2000311
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regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
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Cellular Component |
GO:0016021
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integral component of membrane
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GO:0032281
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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
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PDB ID |
MGI:1859165
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InterPro |
IPR004031
PMP-22/EMP/MP20/Claudin superfamily
IPR008368
Voltage-dependent calcium channel, gamma subunit
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PFAM |
PF00822
PF13903
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PRINTS |
PR01792
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9JJV5
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PhosphoSite |
PhosphoSite-Q9JJV5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
54376
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UniGene |
Mm.444212
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RefSeq |
NP_062303
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MGI ID |
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MGI Symbol |
Cacng3
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OMIM |
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CCDS |
CCDS21816
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HPRD |
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IMGT |
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EMBL |
AJ272044
BC138673
BC145971
CH466531
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GenPept |
AAI38674
AAI45972
CAB86385
EDL17281
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