Mus musculus Protein: Napb
Summary
InnateDB Protein IDBP-209036.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Napb
Protein Name N-ethylmaleimide sensitive fusion protein attachment protein beta
Synonyms b-SNAP; Brp14; E161; I47; SNARE;
Species Mus musculus
Ensembl Protein ENSMUSP00000028926
InnateDB Gene IDBG-209032 (Napb)
Protein Structure
UniProt Annotation
Function Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subcellular Localization Membrane; Peripheral membrane protein.
Disease Associations
Tissue Specificity Cerebral cortex, cerebellar cortex, hippocampus, and dentate gyrus, weakly expressed in the putamen, the thalamus and the brain stem. {ECO:0000269PubMed:8455721}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019905 syntaxin binding
Biological Process
GO:0006886 intracellular protein transport
GO:0010807 regulation of synaptic vesicle priming
GO:0035249 synaptic transmission, glutamatergic
GO:0035494 SNARE complex disassembly
Cellular Component
GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex
Protein Structure and Domains
PDB ID MGI:104562
InterPro IPR000744 NSF attachment protein
PFAM PF02071
PRINTS PR00448
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P28663
PhosphoSite PhosphoSite-P28663
TrEMBL
UniProt Splice Variant
Entrez Gene 17957
UniGene Mm.487504
RefSeq NP_062606
MGI ID
MGI Symbol Napb
OMIM
CCDS CCDS16842
HPRD
IMGT
EMBL AK083184 BC038362 BC049874 X61455
GenPept AAH38362 AAH49874 BAC38798 CAA43695