Version 5.4
Mus musculus Protein: Cst12
Summary
InnateDB Protein IDBP-209111.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cst12
Protein Name cystatin 12
Synonyms 1700006F03Rik; CRES3;
Species Mus musculus
Ensembl Protein ENSMUSP00000028932
InnateDB Gene IDBG-209109 (Cst12)
Protein Structure
UniProt Annotation
Function May play a specialized role in spermatogenesis. {ECO:0000269PubMed:12444065}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Located at the very proximal caput epididymis (at protein level). Expressed in epididymis, Sertoli cells and testis. Also found to be weakly expressed in ovary and prostate. {ECO:0000269PubMed:12444065}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004869 cysteine-type endopeptidase inhibitor activity
Biological Process
GO:0008150 biological_process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:1916612
InterPro IPR000010 Proteinase inhibitor I25, cystatin
PFAM PF00031
PRINTS
PIRSF
SMART SM00043
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DAN8
PhosphoSite PhosphoSite-Q9DAN8
TrEMBL
UniProt Splice Variant
Entrez Gene 69362
UniGene Mm.280779
RefSeq
MGI ID
MGI Symbol Cst12
OMIM
CCDS
HPRD
IMGT
EMBL AF440737 AK005670 AL844519 BC119432
GenPept AAI19433 AAL30843 BAB24179 CAM18689

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca