Version 5.4
Mus musculus Protein: G0s2
Summary
InnateDB Protein IDBP-209156.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol G0s2
Protein Name G0/G1 switch gene 2
Synonyms AI255151; AV006465;
Species Mus musculus
Ensembl Protein ENSMUSP00000009777
InnateDB Gene IDBG-209154 (G0s2)
Protein Structure
UniProt Annotation
Function Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers. {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0097191 extrinsic apoptotic signaling pathway
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:1316737
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q61585
PhosphoSite PhosphoSite-
TrEMBL Q545U0
UniProt Splice Variant
Entrez Gene 14373
UniGene
RefSeq NP_032085
MGI ID
MGI Symbol G0s2
OMIM
CCDS CCDS15636
HPRD
IMGT
EMBL AK003165 AL365314 BC117038 BC117040 CH466555 X95280
GenPept AAI17039 AAI17041 BAB22615 CAA64601 EDL12948

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca